What is the prevalence of sickle cell anemia in populations of African descent?

2020-02-27

What is the prevalence of sickle cell anemia in populations of African descent?

SCD occurs among about 1 out of every 365 Black or African-American births. SCD occurs among about 1 out of every 16,300 Hispanic-American births. About 1 in 13 Black or African-American babies is born with sickle cell trait (SCT).

Is Sickle cell anemia common in Ghana?

Sickle Cell Disease (SCD) is a significant public health burden in Ghana. Recent studies indicate that 2% of Ghanaian newborns are affected by SCD; one in three Ghanaians has the hemoglobin S and/or C gene.

Which ethnic group has the highest incidence of sickle cell disease?

Sickle cell disease is more common in certain ethnic groups, including: People of African descent, including African-Americans (among whom 1 in 12 carries a sickle cell gene) Hispanic-Americans from Central and South America.

Why is sickle cell disease more common in African descent?

SCD and SCT impact African Americans at disproportionate rates. This is because SCD and SCT are an evolutionary trait that people developed in response to help protect them from malaria. As such, this condition is common in large parts of Africa.

What is the prevalence of sickle cell disease in worldwide?

The global meta-estimate for the birth prevalence of homozygous sickle cell disease was 111.91 per 100 000 live births (95% CI = 100.77-123.05) (Figure 2).

Is stem cell transplant done in Ghana?

Since its establishment in June 2017, BMTG has conducted seven successful bone marrow transplants at the Greater Accra Regional Hospital where the center is located. This was done at the heavily subsidized cost of twenty-five thousand US dollars ($25,000) per patient.

Is bone marrow transplant done in Ghana?

History has been made as the Greater Accra Regional Hospital (Ridge Hospital) has admitted its first patient to undergo the first-ever bone marrow transplant procedure in Ghana at the Bone Marrow Transplant (BMT) centre at the facility.

Is sickle cell only in African American?

Answer. Yes, they can. Sickle cell disease can affect people of ANY race or ethnicity. Sickle cell disease, an inherited disorder of the red blood cells, is more common in African Americans in the U.S. compared to other ethnicities—occurring in approximately 1 in 365 African Americans.