What is the difference between Type 1 and Type 2 myocardial infarction?

2021-06-03

What is the difference between Type 1 and Type 2 myocardial infarction?

For patients with type 1 MI, the focus is on aggressive antithrombotic therapy and consideration of urgent coronary angiography and revascularization. For patients with type 2 MI, the focus is on treating the extracardiac stressor precipitating the myocardial oxygen supply and demand imbalance.

What is a Type 2 myocardial infarction?

Type 2 MI is defined as “myocardial infarction secondary to ischaemia due to either increased oxygen demand or decreased supply, e.g. coronary artery spasm, coronary embolism, anaemia, arrhythmias, hypertension or hypotension.”

Is a Type 2 MI serious?

Type 2 MI is distinguished from myocardial injury without acute ischemia, for example, acute heart failure and myocarditis. Type 2 MI is associated with a poor outcome. Several studies have demonstrated higher mortality rates among patients with type 2 MI as compared with patients with type 1 MI.

How is type 2 myocardial infarction diagnosed?

Background. Type 2 myocardial infarction (MI) is defined by a rise and fall of cardiac biomarkers and evidence of ischemia without unstable coronary artery disease (CAD), due to a mismatch in myocardial oxygen supply and demand. Myocardial injury is similar but does not meet clinical criteria for MI.

How is type 2 MI diagnosed?

Diagnostic criteria for type 2 MI include the following: (1) detection of markers of cardiac myonecrosis (ie, elevated troponin concentrations); (2) clinical context lacking signs or symptoms suggestive of acute coronary syndrome or nonischemic contributors to myocardial injury (such as myocarditis); and (3) …

What are the 5 types of MI?

Five Types of MI Will Make Up New Definition

  • A primary coronary event, such as plaque rupture or dissection.
  • A problem of oxygen supply and demand, such as coronary spasm, coronary embolism, arrhythmia, anemia, or hypotension.

Is type 2 MI considered ACS?

In contrast to MI due to an acute coronary syndrome (type 1 MI), type 2 MI is defined as a mismatch in myocardial oxygen supply and demand that is not attributed to unstable coronary artery disease (CAD).

Do you have chest pain with a Type 2 MI?

Compared with patients with type 1 MI, patients with type 2 MI presented less often with chest pain (42.7% vs 73.9%, P < . 001), and presented more often with dyspnea, although the difference did not reach statistical significance (59.2% vs 51%, P = . 07).

How is type 2 NSTEMI treated?

Type I NSTEMI employs anti-platelet and antithrombotic therapies i.e percutaneous coronary intervention. Treatment of Type II NSTEMI is directed at managing the underlying condition. urgent dialysis for decompensated heart failure.