What is isoniazid used for?
Isoniazid is used to treat tuberculosis (TB) or prevent its return (reactivation). It may be given alone, or in combination with other medicines, to treat TB or to prevent its return (reactivation). This medicine may also be used for other problems as determined by your doctor.
What is INH called?
Isoniazid, also known as isonicotinic acid hydrazide (INH), is an antibiotic used for the treatment of tuberculosis….Isoniazid.
| Clinical data | |
|---|---|
| Other names | isonicotinic acid hydrazide, isonicotinyl hydrazine, INH, INAH, INHA |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a682401 |
| License data | US DailyMed: Isoniazid |
What is isoniazid and rifapentine?
Rifampin and isoniazid combination is used to treat tuberculosis (TB) infection. It may be taken alone or with one or more other medicines for TB. Rifampin belongs to the class of medicines called antibiotics and works to kill or prevent the growth of bacteria.
Why is isoniazid used for TB?
Isoniazid and Rifapentine (INH-RPT) are medicines used together to treat LTBI. They kill the sleeping TB germs before they make you sick. It can take many months for the medicine to kill the TB germs because they are strong.
Is isoniazid safe?
Serious and sometimes fatal liver problems may occur during treatment with isoniazid or after you stop taking this medication, even months after stopping. The risk of liver problems is highest in adults between the ages of 35 and 65.
Is isoniazid a chemotherapy drug?
The role of individual drugs in first-line chemotherapy of TB[31] is unique. Isoniazid is responsible for the initial kill of about 95% organisms during the first two days of treatment. Its bactericidal role is then replaced by rifampicin and pyrazinamide during the intensive phase.
How does isoniazid cure TB?
What is the mechanism of isoniazid?
Mechanism of action — The antimicrobial activity of INH is selective for mycobacteria, likely due to its ability to inhibit mycolic acid synthesis, which interferes with cell wall synthesis, thereby producing a bactericidal effect [1].
When do you take INH?
The ideal time to take your tablets each day is half an hour before breakfast. If you forget, then take the tablets two hours after breakfast or wait until half an hour before your next meal. This is because isoniazid is absorbed better when your stomach is empty.