Should you replace folate before B12?


Should you replace folate before B12?

Folate and B12 should always be assessed together due to the close relationship of metabolism and overlap of clinical symptoms deficiency causes. Indications for folate supplementation without assessment of folate levels are: 1.

How long does it take to replete folate?

The body has about 1,000-20,000 mcg of folate stores, and adults need about 400 mcg/d to replenish the daily losses. Folate deficiency may take 8-16 weeks to become evident.

When do you replace folate?

Treatment of folate deficiency should include: Prescribing oral folic acid 5 mg daily. In most people, treatment will be required for 4 months. Folic acid may need to be taken longer-term (sometimes for life) if the underlying cause of deficiency is persistent.

How do you replace folate deficiency?

Folic acid tablets are used to restore folate levels. These usually need to be taken for four months. In some cases, improving your diet can help treat the condition and prevent it recurring. Vitamin B12 is found in meat, fish, eggs, dairy products, yeast extract (such as Marmite) and specially fortified foods.

Can you give B12 and folate together?

Both folic acid and vitamin B12 are essential for health. But when taken together, these B vitamins may interact with each other. You shouldn’t take more than 1,000 micrograms (mcg.) of supplemental folic acid per day.

Can you get folate in a supplement?

Folate is available in multivitamins and prenatal vitamins. It is also available in B-complex dietary supplements and supplements containing only folate. In dietary supplements, folate is usually in the form of folic acid, but methylfolate (5-methyl-THF) is also used.

What blocks folic acid absorption?

Diseases in which folic acid is not well absorbed in the digestive system (such as Celiac disease or Crohn disease) Drinking too much alcohol. Eating overcooked fruits and vegetables. Folate can be easily destroyed by heat.

Is B12 the same as folate?

Vitamin B12 is an especially important vitamin for maintaining healthy nerve cells, and it helps in the production of DNA and RNA, the body’s genetic material. Vitamin B12 works closely with vitamin B9, also called folate or folic acid, to help make red blood cells and to help iron work better in the body.

Who is most at risk for folate deficiency?

Folate deficiency is most commonly found in pregnant and lactating women, people with chronic conditions of the gastrointestinal tract, people following restricted diets due to weight-loss regimes or medical conditions, people with alcohol dependence and people more than 65 years of age.

Can I take folic acid and vitamin D together?

Vitamin D-3 and folic acid don’t interact negatively with each other, according to the website And taking them together doesn’t seem to have any special benefits. Each, however, is good for you. Before you start taking them regularly, talk with your physician.

Is it OK to take B-12 and folic acid together?